We are proud to have urodynamic facility at out centre.We have one doctor Dr Ashok who is completely dedicated to do the urodynamic studies under the guidance of one of 4 urologists who form the urology team of Ramayya Pramila Hospitals.
Monday, March 25, 2013
METALLIC STENTING FOR OBSTRUCTUVE UROPATHY IN HORMONE REFRACTORY PROSTATE CANCER
A 70 year old patient came to us with hematuria post TUR channeling for carcinoma prostate.He was a case of hormone refractory carcinoma prostate.He had undergone docetaxel based chemotherapy followed by vinorelbine based chemotherapeutic regimen. He had developed painful bone metastases and bilateral pedal lymphoedma because of inguinal/ retroperitoneal lymphadenopathy.His PSA was 76ng/ml and the bone scan was a superscan.
His CT scan revealed retroperitoneal /iliac lymphadenothay and prostate enlargement with clots in the bladder and bilateral HDUN (L>R).
We took him up for completion laser prostatectomy as the bleeding was ongoing.After the surgery the bleeding subsided.We planned the patient for Extandi(Enzalutamide) but because of the cost factor and also the availability; we couldnot do that.In the interim period we started him on Thalidomide 100 mg twice a day.
The patient was given samarium radio-isotope therapy for painful bony metastases.His creatinine was rising from 1.1 mg% to 3.3 mg% and was explained the need for DJ stenting.
We couldnot do DJ stenting from below (as we expected because of subtrigonal infiltration by the tumor) and antegrade stenting with Cook metallic stent was done.On left side the stenting could not be done because of multiple kinks and decision was taken not to go ahead with nephrostomy as it would cripple his quality of life.
| DIRECT PELVIC PUNCTURE FOR DELINEATION OF PELVICALYCEAL ANATOMY |
| METALLIC STENT ASSEMBLY |
| WITH THE USE OF MICRONEPHROSCOPE INSERTION OF GUIDE WIRE INTO THE BLADDER ANTEGRADELY |
| GUIDE WIRE PULLED OUT FROM THE BLADDER WITH THE CYSTOSCOPE AND METALLIC STENT BEING PLACED |
| METALLIC STENT BEING PLACED |
His creatinine progressively came down to 1.4 mg% and got stabilised there.He is being planned for Zytiga(Abiraterone acetate) after a gap of 1 week.
Obstructive uropathy secondary to advanced prostate cancer varies
between 3.3 and 16%. Historically, the prognosis
for patients in the psychological situation is poor.
Obstructive uropathy secondary to prostate cancer is associated with a
significant reduction in global survival in comparison with patients with
prostate cancer without obstruction. Advanced disease stage is significantly
correlated with development of obstructive uropathy.
In accordance to this and the bibliographic review, recommendation may be
established that every patient should be candidate for nephrostomy
disregarding his hormonal status and that nephrostomy
tube should be inserted, if indicated, as soon as possible to avoid an increase
in mortality secondary to the complications of uremia.
Prior to a
possible therapeutic abstention it should be considered if the disease is in
terminal phase without possibility of curative treatment, with a high analgesia
requirements and bad general status (Karnofsky
index).
As this patients karnofsky performance index was good and his biochemical and hematological parameters were well maintainend ; we decided to go for metallic stenting , samarium therapy for bony metastases and Zytiga for the checking the progression of the disease.
VASOEPIDIDYMOSTOMY: ANOTHER CASE WE DID TODAY
A 30 year old gentleman came from Orissa for treatment of azoospermia.
He had a semen analysis done which showed 1.5 ml quantity and nil count with semen culture positive for enterococcus.He gave occasional history of perineal pain.
He did not have any sexual dysfunction and comorbdities.He was not on any chronic medications.
He was evaluated for azoospermia and found to have normal reproductive hormones assay. Trans Rectal ultrasound examination also revealed normal seminal vesicular anatomy.His USG doppler revealed bilateral grade 1 -2 variocele.
He was taken up for VEA ; before the proedure we did epididymal aspiration and found to have abundant motile sperms under microscopy.
Bilateral microsurgical VEA with Berger's two suture intusussepting technique was done.
PSYCHOGENIC SEXUAL DYSFUNCTION:OVERVIEW
Definition
A disturbance of sexual functioning, such as impotence, premature ejaculation, or anorgasmy, that may be caused by one's mental and emotional difficulties concerning sexuality rather than physical disorders.
Causes
Psychosexual dysfunction is a sexual dysfunction that is due to psychological causes rather than physical problems, medical illnesses, or the side effects of medication.
Some of the
psychological conditions include:
- stress or anxiety from work or family responsibilities
- anxiety about sexual performance
- conflicts in the relationship with your partner
- depression/anxiety
- unresolved sexual orientation issues, guilty feelings
- previous traumatic sexual or physical experience ( abuse, rape)
- Negative body image and self-esteem problems
- worry or fear about sexually transmitted diseases
- Interpersonal relationship causes may include:
- partner performance and technique/lack of a partner
- relationship quality and conflict
- lack of privacy
Socio-cultural influence causes may
include:
- inadequate education
- conflict with religious, personal, or family values
- societal taboos
Risk
Factors
Reduced sexual desire or activity is very
common among men. Often, the condition is treatable, but first it is necessary
to determine whether the dysfunction is caused by physical causes (such
as diabetes , heart disease , alcoholism ,
heavy smoking, side effects of medications (a very common cause of decreased
libido or desire), or hormonal problems or psychological causes.
Only sexual
dysfunction due to psychological factors is called psychosexual dysfunction.
Symptoms
Symptoms of psychosexual disorder may
differ for men and women.
Symptoms for men include:
- Not able to keep an erection
- Ejaculations are premature
- Ejaculations do not occur
- Not able to become aroused when appropriately stimulated
- Not able to achieve orgasm
- Inhibited sexual desire
Diagnosis
The doctor will ask about the symptoms,
medical history, and sexual history. The doctor will also perform a physical
exam. The doctor to ensure asking about all the medications that are currently being
taken. Questions about the partner
should also be asked..
Tests may include the following:
- Blood tests to check for problems in your hormones or blood vessels (arteries and veins)
- Test testosterone level. Testosterone is the hormone that creates sexual desire in both men and women.
- Depression scale to measure depression
- Mini mental state examination (MMSE)
- A test to gauge mental awareness and judgment (also known as cognitive functioning)
- Additional tests for men:
- NPTR test: to find out basically the ause of erectile dysfunction whether it is psychogenic or organic
- Vascular assessment— The doctor needs to make sure the blood flow to the penis is sufficient: It is mostly done by pharmopenile doppler.In our clinic we sometimes prefer to do Pharmacologically Induced Penile Injetion(PIPE test).Some people also conduct sildenafil office test if patient is scary about penile injection.
Treatment
The most appropriate treatment will depend
on the cause of the psychosexual dysfunction.
Some medications can alleviate the symptoms
(for example, medications to alleviate erectile dysfunction). However, to successfully
manage psychosexual dysfunction, it is important to treat and manage the mental
and emotional issues that underlie the problem.
Treatment options for psychosexual
dysfunction include the following:
Medication
Medications may be prescribed to treat the
symptoms:
For premature ejaculation-Medications in
the SSRI family, such as paroxetine, depoxetine have been shown effective. They
may be used on a daily basis, or several hours prior to intercourse.
Anesthetic creams may be useful and usage
of double condoms may reduce sensations thereby prolonging ejaculation.
Psychotherapy
Patient talk and work with a psychiatrist, sexologist, urologist, psychologist, to figure out ways to deals with stressful or
painful issues.
Sex Therapy
Sex therapists assist you by encouraging
communications, teaching you about sexual fantasies, and helping you focus on
sexual stimuli.
Behavioral Therapy
A psychiatrist, psychologist, social worker
or licensed counselor works with patients to unlearn automatic behaviors.
Marriage or Relationship Counseling
Couples meet with a psychologist, sexologist
or other type of mental health professional to discuss issues, including
communications problems.
Some Psychological Treatment Techniques
of Premature Ejaculation
Premature ejaculation is sometimes a
symptom of anxiety. The amelioration of anxiety by such techniques as
relaxation, desensitization, and assertive training has therefore proved
helpful in certain instances. Some essentially simple tricks may occasionally meet
with gratifying success. For instance, some individuals have managed to delay
orgasm and ejaculation merely by dwelling on non-erotic thoughts and images
while engaged in sexual intercourse. Others have found it more effective to
indulge in self-inflicted pain during coitus (e.g., pinching one's leg, biting
one's tongue).
Masters and Johnson (1970), however, are not in favor of
distraction techniques. The reduction of tactile stimulation (e.g., by
wearing one or more condoms, or by applying anesthetic ointments to the glans
penis) is also often recommended. All of the foregoing procedures are of
limited value (Lazarus, 1978).
- Two very effective techniques for the treatment of premature ejaculation are the pause (Semans, 1956) and the squeeze (Masters and Johnson, 1970) procedures. The pause technique consists of the female stimulating the male manually until he feels the physical sensations immediately preceding orgasm. At this point, the wife stops stimulating him until the sensations subside, then begins stimulating the penis again, and stops just before ejaculation. As this procedure is repeated, the male begins to develop ejaculatory control. The next step consists of repeating the procedure with the penis lubricated, so that the intravaginal environment is more closely approximated.
- Masters and Johnson (1970) have developed a modification of this procedure in which the wife manually stimulates the penis until it becomes erect. She then squeezes the penis at the coronal ridge for three to four seconds, which causes the man to lose the urge to ejaculate and to lose 10-30% of his erection. The wife waits fifteen to thirty seconds, then repeats the procedure. After practicing for a few days, the couple repeats the procedure with intravaginal containment of the penis, but no thrusting, to produce stimulation. The next steps are intravaginal containment with slow movement, and than fast movement, using the squeeze as before.
Prevention
There are no known ways to prevent
psychosexual dysfunction.
To help reduce the chances of developing psychosexual dysfunction:
- Stay aware of the psychological or emotional health.
- Talk to the doctor or mental health provider if you feel the problems surfacing again, you are experiencing excessive stress, or you anticipate a stressful situation in the near future.
- Spend time alone with the partner often, especially nonsexual intimate time, to help maintain the relationship. This will most likely lead to increase sexual interest.
- Continue to communicate openly with the partner about intimacy and sexual issues.
Sunday, March 24, 2013
COMPLETE STONE CLEARANCE PACKAGE AT RAMAYYAS PRAMILA HOSPITALS: LEFT PCNL AND RIGHT ESWL IN THE FIRST SETTING FOLLOWED BY RIGHT RIRS FOR CLEARANCE OF RESIDUAL FRAGMENTS
A 65 year old lady came with left partial staghorn calculus; bulk mainly in upper calyceal group.There was a calculus of around 2 cm in right middle calyx and right renal pelvis. Her urine culture was positive for klebsiella and creatinine level was 3 mg%. Our nephrologist started the patient on imipenam group of the drug and advised to delay surgery for 72 hours till culture was sterile for the safety of the surgery and avoid post operative flare of the infection.
She was taken up for right DJ stenting and left PCNL. Her left ureter was kinked at the PUJO and so could not pass ureteric catheter beyond the PUJO. We punctured the system by stone guided method and introduced micro-nephroscope to ensure right entry into the calyceal system. After ensuring the good access ; a guide wire was placed and dilatation was carrioed out till 24 Fr and Amplatz sheath was introduced and stone fragmentation was don with pneumatic lithotripsy. A complete clearance was achieved and 5 FR DJ stent was placed antegradely at the end of the PCNL procedure.
| USE OF MICROPERC TO ENSURE ENTRY INTO DESIRED CALYX |
Her post operative stay was uneventful and marked by steady decline in the values of serum creatinine till 1.3 mg%. She was taken up for ESWL right side after a period of 2 weeks.there was a good fragmentation and clearance of the calculus .After further 2 weeks , we took patient up for secondary RIRS and the residual calculi were also cleared.
WE ENSURE COMPLETE CLEARANCE OF THE CALCULI AND ROUTINELY DO IMAGING -CT SCAN AND START METABOLIC WORK UP AND PREVENTIVE MEASURES FOR PREVENTING FUTURE RECURRENCE.WE ARE EQUIPPED WITH STATE OF THE ART EQUIPMENTS TO ENSURE COMPLICATION FREE SURGERIES FOR THE SAME.
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