Naftopidil is one new moleculethat has evoked renewed interest in pharmacotherapy for benign prostatic hyperplasia.It is a alpha 1 d receptor antagonist and inhibits significantly cell proliferation dose dependently in all cell lines that expresses alpha (1 d)-AR mRNA .It is said to be effective in sexually active men and those with irritative voiding symptoms..
It has been seen to reduce the nocturnal urine volume and hence cause less disturbance in sleep pattern.
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