Role of Interferon in mumps orchitis

In andrological practice it is common practice to see mumps orchitis or infertility due to mumps orchitis.
In men orchitis represents the most common complication of mumps infection and occurs in 5 to 37% of this population. Bilateral manifestation is observed in 16 to 65% of the patients. The most important danger is the risk of testicular atrophy which results in sterility.
There are conflicting reports of role of systematic interefron-alpha-2 B in mumps orchitis.Some studies supporting its usage and some disputing its utility.
The usual dosage is 3 Millions units administered daily parenterally intravenous form for 7 days. Keeping in view with the low complication rate with systemic interferon therapy (flu like symptoms which can be tackled by paracetamol administration) the andrology department here uses this therapy and strongly advocates it in case of bilateral affection of the testes.