Friday, November 7, 2014

URINE INCONTINENCE AMONG WOMEN:TITBITS FROM URO-GYNECOLOGIST






Urinary incontinence is a very common urinary problem in female patients, and one in three women over the age of 60 years are estimated to have bladder control problems. One reason why women are more affected is the weakening of pelvic floor muscles by childbirth.

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They present with urine leak having great impact on quality of life in the sense of social , occupational,sexual & psycological.Urinary incontinence almost always results from an underlying treatable medical condition but is under-reported to medical practitioners

TYPES:

                                     

STRESS URINARY INCONTINENCE:
Stress urinary incontinence is caused by loss of support of the urethra which is usually a consequence of damage to pelvic support structures as a result of childbirth.
It is characterized by leaking of small amounts of urine with activities which increase abdominal pressure such as coughing, sneezing and lifting. 

URGE URINARY INCONTINENCE:
Involuntary loss of urine occuring for no apparent reason with feeling of urgency.Urge urinary incontinence is caused by uninhibited contractions of the detrusor muscle. It is characterized by leaking of large amounts of urine in association with insufficient warning to get to the bathroom in time.
       
MIXED  URINARY INCONTINENCE:
Stress + urge urinary incontinence

OVERFLOW  URINARY INCONTINENCE:
Involuntary loss of urine from an overtly full bladder ,in absence of any urge to urinate.


PHYSIOLOGY:
During urination, detrusor muscles in the wall of the bladder contract, forcing urine out of the bladder and into the urethra. At the same time, sphincter muscles surrounding the urethra relax, letting urine pass out of the body. Incontinence will occur if the bladder muscles suddenly contract (detrusor muscle) or muscles surrounding the urethra suddenly relax (sphincter muscles).

HOW TO DIAGNOSE ?:
Patients with incontinence should be referred to a medical practitioner specializing in this field.Urologists specialize in the urinary tract, and some urologists further specialize in the female urinary tract.

 A uro-gynecologist is a gynecologist who has special training in urological problems in women or female urologist with special expertise in gynecological diseases causing urine problems.
 Family physicians and internists see patients for all kinds of complaints, and are well trained to diagnose and treat this common problem. These primary care specialists can refer patients to urology specialists if needed.
Other important points include straining and discomfort, use of drugs, recent surgery, and illness.
The physical examination will focus on looking for signs of medical conditions causing incontinence, such as tumors that block the urinary tract, stool impaction, and poor reflexes or sensations, which may be evidence of a nerve-related cause.
A test often performed is the measurement of bladder capacity and residual urine for evidence of poorly functioning bladder muscles.
Other tests include:
Stress test – the patient relaxes, then coughs vigorously as the doctor watches for loss of urine
Urinanalysis– urine is tested for evidence of infection, urinary stones, or other contributing causes.
Blood tests – blood is taken, sent to a laboratory, and examined for substances related to causes of incontinence.
Ultrasound– sound waves are used to visualize the kidneys, ureters, bladder, and urethra.
Cystoscopy – a thin tube with a tiny camera is inserted in the urethra and used to see the inside of the urethra and bladder.
Uro-dynamic study– various techniques measure pressure in the bladder and the flow of urine.
Patients are often asked to keep a diary for a day or more, up to a week, to record the pattern of voiding, noting times and the amounts of urine produced.

It can be diagnosed with symptoms , physical examination, urine examination,by an experienced uro-gynecologist .The diagosis may be further confirmed by  cystocopy and/or urodynamic study.

TREATMENT:
Different types of incontinence require different treament modalities.
                               
Treatment options range from conservative treatment, behaviour management, bladder retraining,pelvic floor therapy,, medications and surgery. The success of treatment depends on the correct diagnoses. Weight loss is recommended in those who are obese.

                                          
Exercising the muscles of the pelvis such as with kegel exercises are a first line treatment for women with stress incontinence.
Efforts to increase the time between urination, known as bladder training, is recommended in those with urge incontinence. Both these may be used in those with mixed incontinence.
                                               
A number of medications exist to treat incontinence including:fesoterodine,oxybutynin.Medications are not recommended for those with stress incontinence and are only recommended in those who have urge incontinence who do not improve with bladder training.
Surgery may be used to alleviate incontinence after other treatments have been tried and found not to be effective

 Stress urinary incontinence requires transvaginal tape surgery.

The tension-free transvaginal tape(TVT) sling procedure treats urinary stress incontinence by positioning a polypropylene mesh tape underneath the urethra. The 20-minute outpatient procedure involves two miniature incisions and has an 86-95% cure rate. The transobturator tape (TOT) sling procedure aims to eliminate stress urinary incontinence by providing support under the urethra
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Urge incontinence mostly treated by medications like Anti -cholinergics.

Overflow incontinence requires to relieve bladder outlet obstruction.

ALWAYS A TEAM OF EXPERTS IS MORE RELIABLE





Wednesday, November 5, 2014

URO-MAP( MINIMAL ACCESS PROCEDURES IN UROLOGY) WORKSHOP FOR UROLOGISTS IN THE STATE HELD AT RAMAYYA PRAMILA UROLOGY AND LAPAROSCOPY HOSPITAL

We are glad to announce that our prostate surgery workshop held on 2nd nov-2014 has been a run away success among the budding and practicing urologists.

We have selected 3 modalities of prostate surgery for BPH(Benign prostate hypertrophy)




  1. THULIUM LASER
  2. HOLMIUM LASER 
  3. TURIS
The workshop was graced by veteran Dr.Vyas narayana rao, a well known,respected and accomplished urologist who formally inaugurated the workshop at 10.00AM on 2nd nov 14.
The first case was done by DR.RAMESH RAMAYYA using thulium laser (REVOLIX).The patient is a known case of mild mitral regurgitation with 150gm prostate.
He was administered combined spinal and epidural anaesthesia and the surgery was well demonstrated with simultaneous question answer session from the visiting urologists with DR.RAVI KUMAR co-ordinating from the auditorium to OT. The surgery concluded in 2.5 hrs and the prostate chips morcellated succesfully with RWOLF morcellator and 2 way 18F foley catheter was inserted and received wide spread applause from the audience.


There was a talk by expert engineer MR.RAJIV BHINDRA who detailed about the physics of lasers and urologist must-know tips on laser benefits and precautions to be taken with laser prostatectomy.
The talk was followed by delicious lunch appreciated by all delegates.

The post lunch session started with 2nd case of 80gm prostate.DR.MALLIKARJUN REDDY was the operating surgeon using Luminous Holmium laser.There was healthy discussion between the surgeon and audience comparing the two lasers in doing effective prostatectomy.The surgery went well and ended with morcellation of prostate lobes and 18F foley 2way catheter.


The 3rd case was a patient with high PSA(Prostate specific antigen) of 10.5 and 50 gm prostate posted for TRUS Biopsy(trans rectal ultra sound) along with TURIS(Trans urethral resection of prostate in saline) using bipolar cautery.The trus was excellently demonstrated by senior radiologist DR.SASHIDHAR PRASAD who cleared common doubts of delegates while doing the procedure.

The TURIS resection of prostate was performed by DR.SARANGAM a senior urologist from warangal,Telangana.The surgery was neatly done and discussed the cost-effectiveness of the TURIS over lasers.

The workshop which had 50 urologists attending was widely apprciated by one and all and ended with Vote of thanks by DR.T.SHIVAPRASAD,Hospital superintendant and anaesthesiologist.There was a request for another workshop by the MCH/DNB urologists in february 2015 which was approved and promised by the RAMAYYA PRAMILA UROLOGY AND LAPAROSCOPY HOSPITAL TEAM.










Tuesday, March 18, 2014

SORAFENIB IN ADVANCED RENAL CELL CARCINOMA

A 50 Year old gentleman presented with caudate lobe metastases after 1 year of left radical nephrectomy and IVC thrombectomy.
The patient had also IVC involvement as diffuse thickening at the hepatic veins confluence.As the recurrence was appearing irresectable a plan was made to start sorafenib 200 mg twice a day and review with MRI scan after a period of 3 months.
Sorafenib has been approved for treatment of advanced renal cell carcinoma.An article in New England Journal of Medicine published January 2007, showed compared with placebo, treatment with sorafenib prolongs progression free survival in patients with advanced clear cell renal cell carcinoma in whom previous therapy has failed. The median progression-free survival was 5.5 months in the sorafenib group and 2.8 months in the placebo group.
It works with inhibition of tyrosine kinase and Raf kinase pathways.
There are many side effects of this molecule. Our patient developed a strong hand and foot syndrome for which the drug had to be stopped temporarily.He developed rectal bleed too.
Other side effects that have been documented are hypophosphatemia,thrombocytepenia,anemia , altered liver enzymes .
We have decided to stop sorafenib temporarily till the hand and foot syndrome resolves and then to reintroduce the medication in low dosage .If the patient tolerates the drug then reinstitute the drug therapy in full dosage.

      

Monday, March 17, 2014

RAMAYYA PRAMILA HOSPITAL DOCTORS BAG FIRST PRIZE AT EUSC2013

Our doctors presented a paper on " Thulium Laser vaporization and enucleation in patients on antiplatelets and anticoagulants" in the 2 nd Annual Emirates Urological Society Conference held at Abudhabi..
A total of 250 patients were included in study and the outcome was very favourable insptite of patients being prone to bleeding and cardiac events during and post-operatively.
The paper was highly appreciated and conferred on 1 st prize.
  

Monday, December 2, 2013

UROFLOWMETRY - THE BEST SCREENING TEST IN UROLOGY


                  Uroflowmetry is a simple, noninvasive, reliable, repeatable and cost effective investigation to screen for and diagnose lower urinary tract abnormalities. Any person suffering from various urinary disturbances need this simple test to look for any abnormalities in voiding. In this test, one has to pass urine in a specialised funnel that is connected to a flow sensor.
  • Elderly(>50 y) men undergoing non-urological surgeries may have underlying bladder outlet obstruction secondary to prostatomegaly. 
  • Healthy men above 50 y also need this test as a part of general health checkup to identify obstruction at an early stage so that it complications like renal failure, retention, stones, bleeding and infections can be prevented.
  • People with symptoms can be better assessed by this test and the treatment can be significantly guided by the findings on this test.
Uroflowmetry Machine







Normal pattern - to severely impaired flow patterns
Intermiitency