Tuesday, July 5, 2011
FINASTERIDE GIVEN FOR HAIR REGROWTH MAY LEAD TO MALE INFERTILITY
Recently a 27 year old gentleman came to us with severe oligospermia.He was a case of hair transplant on finast low dose.There was no other cause discernible for oligospermia.He was asked to stop finast and at the same time advised to take anti-oxidnats to increase the sperm count.He was requested to come after a period of 3 months with fresh report of semen analysis.
Androgenetic alopecia (male pattern hair loss) is caused by androgen-dependent miniaturization of scalp hair follicles, with scalp dihydrotestosterone (DHT) implicated as a contributing cause. Finasteride, an inhibitor of type II 5alpha-reductase, decreases serum and scalp DHT by inhibiting conversion of testosterone to DHT.It is usually given in the low dose of 1 mg/day for accentuating the hair growth in the male pattern baldness.It has been argued that the finasteride doesnot affect spermatogenesis in normal health men in low dosage.But it might affect if the person who is taking the medications has already compromised spermatogenesis.
As most of the patients undegoing treatment for hair regrowth are in the younger age group.The treating surgeon/physician/dermatologist should take into his/her account his fertility status.
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