As many as 50–80% of women in the general population acquire at least 1 UTI during their lifetime. Approximately 7% of patients require hospitalization.Around 20–30% of pregnant women with asymptomatic bacteriuria subsequently develop pyelonephritis. Between 1 year and ~50 years of age, UTI and recurrent UTI are predominantly diseases of females.
It has been estimated that around 8.3 million doctor visits all over the world are for the UTI. It constitutes the second most common type of infection in the body.
The most common strategy employed for UTI prevention is chemoprophylaxis where low dose continuous suppressive antibiotics are administered to the patient.A natural protection against a broad range of uropathogenic microorganisms is there now available in the form of cranberry juice or its extract.
Many a times UTI in pregnancy poses a problem and also lactating mothers because there are limited antibiotics that Urologist can try.In such cases these natural protectants can be a handy tool for urologists.
There are now medications available where cranberry juice extract is combined with D-mannose.
Cranberry juice extract condensed tannins or proanthocyanidins exhibiting anti-adhesion properties.The juice can be taken around 250 ml/day.As it a low calorie drink; it is convenient for females who are diet conscious.This drink is available in India commonly in supermarkets.
The repeated UTIs are due to adherence of bacteria to the cells of the genitourinary tract with their hair like fimbriae. D. Mannose works by coating free floating E. Coli and prevents it from attaching to the epithelium of the genitourinary tract.